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Antiproliferative Activity of a New Quinazolin-4(3H)-One Derivative via Targeting Aurora Kinase A in Non-Small Cell Lung Cancer

Non-small cell lung cancer (NSCLC) is the most common lung cancer subtype. Although chemotherapy and targeted therapy are used for the treatment of patients with NSCLC, the survival rate remains very low. Recent findings suggested that aurora kinase A (AKA), a cell cycle regulator, is a potential ta...

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Detalles Bibliográficos
Autores principales: Lee, Ji Yun, Yang, Huarong, Kim, Donghwa, Kyaw, Kay Zin, Hu, Ruoci, Fan, Yanhua, Lee, Sang Kook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228987/
https://www.ncbi.nlm.nih.gov/pubmed/35745617
http://dx.doi.org/10.3390/ph15060698