HPMA Copolymer Mebendazole Conjugate Allows Systemic Administration and Possesses Antitumour Activity In Vivo

Mebendazole and other benzimidazole antihelmintics, such as albendazole, fenbendazole, or flubendazole, have been shown to possess antitumour activity, primarily due to their microtubule-disrupting activity. However, the extremely poor water-solubility of mebendazole and other benzimidazoles, result...

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Detalles Bibliográficos
Autores principales: Studenovský, Martin, Rumlerová, Anna, Kovářová, Jiřina, Dvořáková, Barbora, Sivák, Ladislav, Kostka, Libor, Berdár, Daniel, Etrych, Tomáš, Kovář, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229042/
https://www.ncbi.nlm.nih.gov/pubmed/35745774
http://dx.doi.org/10.3390/pharmaceutics14061201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229042/
https://www.ncbi.nlm.nih.gov/pubmed/35745774
http://dx.doi.org/10.3390/pharmaceutics14061201

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