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Implementation of QbD Approach to the Analytical Method Development and Validation for the Estimation of Metformin Hydrochloride in Tablet Dosage Forms by HPLC

The current studies entail quality by design (QbD)-enabled development of a simple, rapid, precise, accurate, and cost-effective high-performance liquid chromatographic method for estimation of metformin hydrochloride (M-HCl). Design of experiments (DoE) was applied for multivariate optimization of...

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Detalles Bibliográficos
Autores principales: Sha’at, Mousa, Spac, Adrian Florin, Stoleriu, Iulian, Bujor, Alexandra, Cretan, Monica Stamate, Hartan, Mihaela, Ochiuz, Lacramioara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229060/
https://www.ncbi.nlm.nih.gov/pubmed/35745760
http://dx.doi.org/10.3390/pharmaceutics14061187