Impact of the Gram-Negative-Selective Inhibitor MAC13243 on In Vitro Simulated Gut Microbiota

New Gram-negative-selective antimicrobials are desirable to avoid perturbations in the gut microbiota leading to antibiotic-induced dysbiosis. We investigated the impact of a prototype drug (MAC13243) interfering with the Gram-negative outer membrane protein LolA on the faecal microbiota. Faecal sus...

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Detalles Bibliográficos
Autores principales: Svanberg Frisinger, Frida, Pirolo, Mattia, Ng, Duncan Y. K., Mao, Xiaotian, Nielsen, Dennis Sandris, Guardabassi, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229071/
https://www.ncbi.nlm.nih.gov/pubmed/35745650
http://dx.doi.org/10.3390/ph15060731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229071/
https://www.ncbi.nlm.nih.gov/pubmed/35745650
http://dx.doi.org/10.3390/ph15060731

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