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Comprehensive bioinformatic analysis reveals a cancer-associated fibroblast gene signature as a poor prognostic factor and potential therapeutic target in gastric cancer

BACKGROUND: Gastric cancer is one of the deadliest cancers, currently available therapies have limited success. Cancer-associated fibroblasts (CAFs) are pivotal cells in the stroma of gastric tumors posing a great risk for progression and chemoresistance. The poor prognostic signature for CAFs is no...

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Detalles Bibliográficos
Autores principales: Ucaryilmaz Metin, Cemre, Ozcan, Gulnihal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229147/
https://www.ncbi.nlm.nih.gov/pubmed/35739492
http://dx.doi.org/10.1186/s12885-022-09736-5