In Vitro Anticancer Activity Screening of Novel Fused Thiophene Derivatives as VEGFR-2/AKT Dual Inhibitors and Apoptosis Inducers

Protein kinases are seen as promising targets in controlling cell proliferation and survival in treating cancer where fused thiophene synthon was utilized in many kinase inhibitors approved by the FDA. Accordingly, this work focused on adopting fused thienopyrrole and pyrrolothienopyrimidine scaffol...

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Detalles Bibliográficos
Autores principales: Abdelnaby, Rana M., El-Malah, Afaf A., FakhrEldeen, Rasha R., Saeed, Marwa M., Nadeem, Rania I., Younis, Nancy S., Abdel-Rahman, Hanaa M., El-Dydamony, Nehad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229165/
https://www.ncbi.nlm.nih.gov/pubmed/35745619
http://dx.doi.org/10.3390/ph15060700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229165/
https://www.ncbi.nlm.nih.gov/pubmed/35745619
http://dx.doi.org/10.3390/ph15060700

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