Effects of Flow Hydrodynamics and Eye Movements on Intraocular Drug Clearance

New in vitro prototypes (PK-Eye™) were tested with and without eye movement to understand diffusion and convection effects on intraocular clearance. Port placement in front ((i) ciliary inflow model) and behind the model lens ((ii) posterior inflow model) was used to study bevacizumab (1.25 mg/50 µL...

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Detalles Bibliográficos
Autores principales: Velentza-Almpani, Angeliki, Ibeanu, Nkiruka, Liu, Tianyang, Redhead, Christopher, Tee Khaw, Peng, Brocchini, Steve, Awwad, Sahar, Bouremel, Yann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229170/
https://www.ncbi.nlm.nih.gov/pubmed/35745839
http://dx.doi.org/10.3390/pharmaceutics14061267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229170/
https://www.ncbi.nlm.nih.gov/pubmed/35745839
http://dx.doi.org/10.3390/pharmaceutics14061267

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