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Bisimidazolium Salt Glycosyltransferase Inhibitors Suppress Hepatocellular Carcinoma Progression In Vitro and In Vivo

Hepatocellular carcinoma is a leading cause of cancer death, and the disease progression has been related to glycophenotype modifications. Previously synthesized bisimidazolium salts (C20 and C22) have been shown to selectively inhibit the activity of glycosyltransferases in cultured cancer cell hom...

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Detalles Bibliográficos
Autores principales: Luan, Xue, Sun, Ming, Zhao, Xue, Wang, Jingyi, Han, Ye, Gao, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229238/
https://www.ncbi.nlm.nih.gov/pubmed/35745636
http://dx.doi.org/10.3390/ph15060716