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VEGF Overexpression Significantly Increases Nanoparticle-Mediated siRNA Delivery and Target-Gene Downregulation

The availability of nanoparticles (NPs) to deliver small interfering RNA (siRNA) has significantly expanded the specificity and range of ‘druggable’ targets for precision medicine in cancer. This is especially important for cancers such as triple negative breast cancer (TNBC) for which there are no...

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Detalles Bibliográficos
Autores principales: Tan, Shanshan, Chen, Zhihang, Mironchik, Yelena, Mori, Noriko, Penet, Marie-France, Si, Ge, Krishnamachary, Balaji, Bhujwalla, Zaver M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229257/
https://www.ncbi.nlm.nih.gov/pubmed/35745832
http://dx.doi.org/10.3390/pharmaceutics14061260