The Ameliorative Effect of Empagliflozin in Vigabatrin-Induced Cerebellar/Neurobehavioral Deficits: Targeting mTOR/AMPK/SIRT-1 Signaling Pathways

Introduction. Vigabatrin (VGB) is an antiepileptic drug that acts to irreversibly inhibit the γ-aminobutyric acid (GABA) transaminase enzyme, elevating GABA levels. Broad studies have established that long-term treatment and/or high doses of VGB lead to variable visual defects. However, little atten...

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Detalles Bibliográficos
Autores principales: Amer, Rabab M., Eltokhy, Amira Kamel, Elesawy, Rasha Osama, Barakat, Amany Nagy, Basha, Eman, Eldeeb, Omnia Safwat, Aboalsoud, Alshimaa, Elgharabawy, Nancy Mohamed, Ismail, Radwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229258/
https://www.ncbi.nlm.nih.gov/pubmed/35744783
http://dx.doi.org/10.3390/molecules27123659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229258/
https://www.ncbi.nlm.nih.gov/pubmed/35744783
http://dx.doi.org/10.3390/molecules27123659

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