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Antigenic Site Immunodominance Redirection Following Repeat Variant Exposure

Human norovirus is a leading cause of acute gastroenteritis, driven by antigenic variants within the GII.4 genotype. Antibody responses to GII.4 vaccination in adults are shaped by immune memory. How children without extensive immune memory will respond to GII.4 vaccination has not been reported. He...

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Detalles Bibliográficos
Autores principales: Lindesmith, Lisa C., Brewer-Jensen, Paul D., Mallory, Michael L., Zweigart, Mark R., May, Samantha R., Kelly, Daniel, Williams, Rachel, Becker-Dreps, Sylvia, Bucardo, Filemón, Allen, David J., Breuer, Judith, Baric, Ralph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229260/
https://www.ncbi.nlm.nih.gov/pubmed/35746763
http://dx.doi.org/10.3390/v14061293