Pharmacophore-Based Discovery of Viral RNA Conformational Modulators

New RNA-binding small-molecule scaffolds are needed to unleash the pharmacological potential of RNA targets. Here we have applied a pharmacophore-based virtual screening approach, seldom used in the RNA recognition field, to identify novel conformational inhibitors of the hepatitis C virus internal...

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Detalles Bibliográficos
Autores principales: Martín-Villamil, María, Sanmartín, Isaías, Moreno, Ángela, Gallego, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229403/
https://www.ncbi.nlm.nih.gov/pubmed/35745667
http://dx.doi.org/10.3390/ph15060748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229403/
https://www.ncbi.nlm.nih.gov/pubmed/35745667
http://dx.doi.org/10.3390/ph15060748

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