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Drugs Targeting the A3 Adenosine Receptor: Human Clinical Study Data
The A3 adenosine receptor (A3AR) is overexpressed in pathological human cells. Piclidenoson and namodenoson are A3AR agonists with high affinity and selectivity to A3AR. Both induce apoptosis of cancer and inflammatory cells via a molecular mechanism entailing deregulation of the Wnt and the NF-κB s...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229414/ https://www.ncbi.nlm.nih.gov/pubmed/35744805 http://dx.doi.org/10.3390/molecules27123680 |