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Human Osteochondral Explants as an Ex Vivo Model of Osteoarthritis for the Assessment of a Novel Class of Orthobiologics

Osteoarthritis (OA) is a highly prevalent joint disease still lacking effective treatments. Its multifactorial etiology hampers the development of relevant preclinical models to evaluate innovative therapeutic solutions. In the last decade, the potential of Mesenchymal Stem Cell (MSC) secretome, or...

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Detalles Bibliográficos
Autores principales: Giannasi, Chiara, Mangiavini, Laura, Niada, Stefania, Colombo, Andrea, Della Morte, Elena, Vismara, Valeria, Ambrosanio, Andrea, Savadori, Paolo, Casati, Sara, Peretti, Giuseppe M., Brini, Anna Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229444/
https://www.ncbi.nlm.nih.gov/pubmed/35745803
http://dx.doi.org/10.3390/pharmaceutics14061231