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Design, Synthesis, and In Vitro Evaluation of Novel 8-Amino-Quinoline Combined with Natural Antioxidant Acids

Overproduction of reactive oxygen species (ROS) and alterations in metallostasis are common and related hallmarks in several neurodegenerative diseases (NDDs). Nature-based derivatives always represent an attractive tool in MTDL drug design, especially against ROS in NDDs. On this notion, we designe...

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Detalles Bibliográficos
Autores principales: Bacci, Andrea, Corsi, Francesca, Runfola, Massimiliano, Sestito, Simona, Piano, Ilaria, Manera, Clementina, Saccomanni, Giuseppe, Gargini, Claudia, Rapposelli, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229476/
https://www.ncbi.nlm.nih.gov/pubmed/35745606
http://dx.doi.org/10.3390/ph15060688