Anticancer Cytotoxic Activity of Bispidine Derivatives Associated with the Increasing Catabolism of Polyamines

Polyamine (PA) catabolism is often reduced in cancer cells. The activation of this metabolic pathway produces cytotoxic substances that might cause apoptosis in cancer cells. Chemical compounds able to restore the level of PA catabolism in tumors could become potential antineoplastic agents. The sea...

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Detalles Bibliográficos
Autores principales: Neborak, Ekaterina V., Kaldybayeva, Altynay B., Bey, Lylia, Malmakova, Aigul Y., Tveritinova, Anna S., Hilal, Abdullah, Yu, Valentina K., Ploskonos, Maria V., Komarova, Marina V., Agostinelli, Enzo, Zhdanov, Dmitry D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229528/
https://www.ncbi.nlm.nih.gov/pubmed/35744995
http://dx.doi.org/10.3390/molecules27123872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229528/
https://www.ncbi.nlm.nih.gov/pubmed/35744995
http://dx.doi.org/10.3390/molecules27123872

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