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Efficient Delivery of Curcumin by Alginate Oligosaccharide Coated Aminated Mesoporous Silica Nanoparticles and In Vitro Anticancer Activity against Colon Cancer Cells

We designed and synthesized aminated mesoporous silica (MSN-NH(2)), and functionally grafted alginate oligosaccharides (AOS) on its surface to get MSN-NH(2)-AOS nanoparticles as a delivery vehicle for the fat-soluble model drug curcumin (Cur). Dynamic light scattering, thermogravimetric analysis, an...

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Detalles Bibliográficos
Autores principales: Liu, Chennan, Jiang, Fangyuan, Xing, Zifeng, Fan, Lihong, Li, Yuan, Wang, Shaoning, Ling, Junhong, Ouyang, Xiao-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229531/
https://www.ncbi.nlm.nih.gov/pubmed/35745738
http://dx.doi.org/10.3390/pharmaceutics14061166