Halogen-Based 17β-HSD1 Inhibitors: Insights from DFT, Docking, and Molecular Dynamics Simulation Studies

The high expression of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) mRNA has been found in breast cancer tissues and endometriosis. The current research focuses on preparing a range of organic molecules as 17β-HSD1 inhibitors. Among them, the derivatives of hydroxyphenyl naphthol steroidomimet...

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Detalles Bibliográficos
Autores principales: Kulandaisamy, Arulsamy, Panneerselvam, Murugesan, Solomon, Rajadurai Vijay, Jaccob, Madhavan, Ramakrishnan, Jaganathan, Poomani, Kumaradhas, Maruthamuthu, Muralikannan, Tharmalingam, Nagendran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229637/
https://www.ncbi.nlm.nih.gov/pubmed/35745085
http://dx.doi.org/10.3390/molecules27123962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229637/
https://www.ncbi.nlm.nih.gov/pubmed/35745085
http://dx.doi.org/10.3390/molecules27123962

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