Antioxidative NAC-Loaded Silk Nanoparticles with Opening Mucosal Tight Junctions for Nasal Drug Delivery: An In Vitro and In Vivo Study

Using nasal routes to deliver drugs to the brain using multifunctional nanoparticles (NPs) to bypass the blood–brain barrier (BBB) might enhance the delivery efficacy. Anti-oxidative N-Acetyl-L-cysteine (NAC)-loaded silk fibroin (SF/NAC) NPs are produced, characterized and studied as a potential del...

Descripción completa

Detalles Bibliográficos
Autores principales: Chung, Tze-Wen, Wu, Ting-Ya, Siah, Zheng-Yu, Liu, Der-Zen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229699/
https://www.ncbi.nlm.nih.gov/pubmed/35745861
http://dx.doi.org/10.3390/pharmaceutics14061288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229699/
https://www.ncbi.nlm.nih.gov/pubmed/35745861
http://dx.doi.org/10.3390/pharmaceutics14061288

Ejemplares similares