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Efficient Catalytic Synthesis of Condensed Isoxazole Derivatives via Intramolecular Oxidative Cycloaddition of Aldoximes

The intramolecular oxidative cycloaddition reaction of alkyne- or alkene-tethered aldoximes was catalyzed efficiently by hypervalent iodine(III) species to afford the corresponding polycyclic isoxazole derivatives in up to a 94% yield. The structure of the prepared products was confirmed by various...

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Detalles Bibliográficos
Autores principales: Mironova, Irina A., Nenajdenko, Valentine G., Postnikov, Pavel S., Saito, Akio, Yusubov, Mekhman S., Yoshimura, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229713/
https://www.ncbi.nlm.nih.gov/pubmed/35744982
http://dx.doi.org/10.3390/molecules27123860