Effect of the ABCA1 agonist CS-6253 on amyloid-β and lipoprotein metabolism in cynomolgus monkeys

BACKGROUND: Inducing brain ATP-binding cassette 1 (ABCA1) activity in Alzheimer’s disease (AD) mouse models is associated with improvement in AD pathology. The purpose of this study was to investigate the effects of the ABCA1 agonist peptide CS-6253 on amyloid-β peptides (Aβ) and lipoproteins in pla...

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Detalles Bibliográficos
Autores principales: Noveir, Sasan D., Kerman, Bilal E., Xian, Haotian, Meuret, Cristiana, Smadi, Sabrina, Martinez, Ashley E., Johansson, Johannes, Zetterberg, Henrik, Parks, Bryan A., Kuklenyik, Zsuzsanna, Mack, Wendy J., Johansson, Jan O., Yassine, Hussein N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229758/
https://www.ncbi.nlm.nih.gov/pubmed/35751102
http://dx.doi.org/10.1186/s13195-022-01028-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229758/
https://www.ncbi.nlm.nih.gov/pubmed/35751102
http://dx.doi.org/10.1186/s13195-022-01028-1

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