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Increased Level of Tim-3(+)PD-1(+)CD4(+)T Cells With Altered Function Might Be Associated With Lower Extremity Arteriosclerosis Obliterans

Lower extremity arteriosclerosis obliterans (LEASO) is a vascular disease that may result in adult limb loss worldwide. CD4(+)T cell-mediated immunity plays a significant role in LEASO. The T cell immunoglobulin and mucin domain 3 (Tim-3) and inhibitory receptor programmed cell death-1 (PD-1) are we...

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Detalles Bibliográficos
Autores principales: Cui, Liyuan, Chen, Lanting, Dai, Yuxin, Ou, JingMin, Qiu, Mingke, Wang, Songcun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229777/
https://www.ncbi.nlm.nih.gov/pubmed/35757718
http://dx.doi.org/10.3389/fimmu.2022.871362