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Increased Level of Tim-3(+)PD-1(+)CD4(+)T Cells With Altered Function Might Be Associated With Lower Extremity Arteriosclerosis Obliterans
Lower extremity arteriosclerosis obliterans (LEASO) is a vascular disease that may result in adult limb loss worldwide. CD4(+)T cell-mediated immunity plays a significant role in LEASO. The T cell immunoglobulin and mucin domain 3 (Tim-3) and inhibitory receptor programmed cell death-1 (PD-1) are we...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229777/ https://www.ncbi.nlm.nih.gov/pubmed/35757718 http://dx.doi.org/10.3389/fimmu.2022.871362 |