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Functional changes of the gastric bypass microbiota reactivate thermogenic adipose tissue and systemic glucose control via intestinal FXR-TGR5 crosstalk in diet-induced obesity

BACKGROUND: Bariatric surgery remains the most effective therapy for adiposity reduction and remission of type 2 diabetes. Although different bariatric procedures associate with pronounced shifts in the gut microbiota, their functional role in the regulation of energetic and metabolic benefits achie...

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Detalles Bibliográficos
Autores principales: Münzker, Julia, Haase, Nadine, Till, Andreas, Sucher, Robert, Haange, Sven-Bastiaan, Nemetschke, Linda, Gnad, Thorsten, Jäger, Elisabeth, Chen, Jiesi, Riede, Sjaak J., Chakaroun, Rima, Massier, Lucas, Kovacs, Peter, Ost, Mario, Rolle-Kampczyk, Ulrike, Jehmlich, Nico, Weiner, Juliane, Heiker, John T., Klöting, Nora, Seeger, Gudrun, Morawski, Markus, Keitel, Verena, Pfeifer, Alexander, von Bergen, Martin, Heeren, Joerg, Krügel, Ute, Fenske, Wiebke K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229785/
https://www.ncbi.nlm.nih.gov/pubmed/35739571
http://dx.doi.org/10.1186/s40168-022-01264-5