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Squalamine and Its Aminosterol Derivatives: Overview of Biological Effects and Mechanisms of Action of Compounds with Multiple Therapeutic Applications

Squalamine is a natural aminosterol that has been discovered in the tissues of the dogfish shark (Squalus acanthias). Studies have previously demonstrated that this promoter compound and its derivatives exhibit potent bactericidal activity against Gram-negative, Gram-positive bacteria, and multidrug...

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Detalles Bibliográficos
Autores principales: Mammari, Nour, Salles, Elsa, Beaussart, Audrey, El-Kirat-Chatel, Sofiane, Varbanov, Mihayl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229800/
https://www.ncbi.nlm.nih.gov/pubmed/35744723
http://dx.doi.org/10.3390/microorganisms10061205