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In Silico, In Vitro, and Pharmacokinetic Studies of UBMC-4, a Potential Novel Compound for Treating against Trypanosoma cruzi

The lack of therapeutic alternatives for the treatment of Chagas disease, a neglected disease, drives the discovery of new drugs with trypanocidal activity. Consequently, we conducted in vitro studies using UBMC-4, a potential Trypanosoma cruzi AKT-like pleckstrin homology (PH) domain inhibitory com...

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Detalles Bibliográficos
Autores principales: Bustamante, Christian, Díez-Mejía, Andrés Felipe, Arbeláez, Natalia, Soares, Maurilio José, Robledo, Sara M., Ochoa, Rodrigo, Varela-M., Rubén E., Marín-Villa, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229894/
https://www.ncbi.nlm.nih.gov/pubmed/35745470
http://dx.doi.org/10.3390/pathogens11060616