Biological Therapy of Severe Asthma with Dupilumab, a Dual Receptor Antagonist of Interleukins 4 and 13

Interleukin-4 (IL-4) and interleukin-13 (IL-13) are key cytokines involved in the pathophysiology of both immune-inflammatory and structural changes underlying type 2 asthma. IL-4 plays a pivotal role in Th2 cell polarization, immunoglobulin E (IgE) synthesis and eosinophil recruitment into the airw...

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Detalles Bibliográficos
Autores principales: Pelaia, Corrado, Pelaia, Giulia, Crimi, Claudia, Maglio, Angelantonio, Armentaro, Giuseppe, Calabrese, Cecilia, Sciacqua, Angela, Gallelli, Luca, Vatrella, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229960/
https://www.ncbi.nlm.nih.gov/pubmed/35746582
http://dx.doi.org/10.3390/vaccines10060974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229960/
https://www.ncbi.nlm.nih.gov/pubmed/35746582
http://dx.doi.org/10.3390/vaccines10060974

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