Nano-Silica Carriers Coated by Chloramphenicol: Synthesis, Characterization, and Grinding Trial as a Way to Improve the Release Profile

Silica nanoparticles were applied as the carrier of chloramphenicol (2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide), and were loaded in a 1% carbopol-based gel (poly(acrylic acid)), which allowed obtainment of an upgraded drug form. The samples of silica materials were...

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Detalles Bibliográficos
Autores principales: Balwierz, Radosław, Bursy, Dawid, Biernat, Paweł, Hudz, Nataliia, Shanaida, Mariia, Krzemiński, Łukasz, Skóra, Paweł, Biernat, Monika, Siodłak, Wioletta Ochędzan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230014/
https://www.ncbi.nlm.nih.gov/pubmed/35745622
http://dx.doi.org/10.3390/ph15060703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230014/
https://www.ncbi.nlm.nih.gov/pubmed/35745622
http://dx.doi.org/10.3390/ph15060703

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