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Ectopic Expression of Plasmodium vivax vir Genes in P. falciparum Affects Cytoadhesion via Increased Expression of Specific var Genes

Plasmodium falciparum-infected erythrocytes (PfIEs) adhere to endothelial cell receptors (ECRs) of blood vessels mainly via PfEMP1 proteins to escape elimination via the spleen. Evidence suggests that P. vivax-infected reticulocytes (PvIRs) also bind to ECRs, presumably enabled by VIR proteins, as s...

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Detalles Bibliográficos
Autores principales: Rehn, Torben, Lubiana, Pedro, Nguyen, Thi Huyen Trang, Pansegrau, Eva, Schmitt, Marius, Roth, Lisa Katharina, Brehmer, Jana, Roeder, Thomas, Cadar, Dániel, Metwally, Nahla Galal, Bruchhaus, Iris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230084/
https://www.ncbi.nlm.nih.gov/pubmed/35744701
http://dx.doi.org/10.3390/microorganisms10061183