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Phosphatidylinositol transfer protein/planar cell polarity axis regulates neocortical morphogenesis by supporting interkinetic nuclear migration

The neocortex expands explosively during embryonic development. The earliest populations of neural stem cells (NSCs) form a thin pseudostratified epithelium whose contour determines that of the adult neocortex. Neocortical complexity is accompanied by disproportional expansion of the NSC layer in it...

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Detalles Bibliográficos
Autores principales: Xie, Zhigang, Bankaitis, Vytas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230501/
https://www.ncbi.nlm.nih.gov/pubmed/35649377
http://dx.doi.org/10.1016/j.celrep.2022.110869