Design of an L-Valine-Modified Nanomicelle-Based Drug Delivery System for Overcoming Ocular Surface Barriers

The incidence of ocular surface disease (OSD) is increasing, with a trend towards younger ages. However, it is difficult for drugs to reach the deep layers of the cornea due to ocular surface barriers, and bioavailability is less than 5%. In this study, DSPE-PEG2000 was modified with L-valine (L-Val...

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Detalles Bibliográficos
Autores principales: Wu, Huimin, Xu, Yuchen, Cai, Mengru, You, Longtai, Liu, Jing, Dong, Xiaoxv, Yin, Xingbin, Ni, Jian, Qu, Changhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230556/
https://www.ncbi.nlm.nih.gov/pubmed/35745853
http://dx.doi.org/10.3390/pharmaceutics14061277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230556/
https://www.ncbi.nlm.nih.gov/pubmed/35745853
http://dx.doi.org/10.3390/pharmaceutics14061277

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