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Enhanced Solubility and Antitumor Activity of Annona Squamosa Seed Oil via Nanoparticles Stabilized with TPGS: Preparation and In Vitro and In Vivo Evaluation

Annona squamosa seed oil (ASSO), which is a waste product in the extraction of annonaceous acetogenins (ACGs), displays good antitumor activity against a variety of tumor cells. However, ASSO is insoluble and has low bioavailability. In order to improve the solubility and application value of ASSO,...

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Detalles Bibliográficos
Autores principales: Ao, Hui, Lu, Likang, Li, Manzhen, Han, Meihua, Guo, Yifei, Wang, Xiangtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230568/
https://www.ncbi.nlm.nih.gov/pubmed/35745804
http://dx.doi.org/10.3390/pharmaceutics14061232