Impact of Nitisinone on the Cerebrospinal Fluid Metabolome of a Murine Model of Alkaptonuria

Background: Nitisinone-induced hypertyrosinaemia is well documented in Alkaptonuria (AKU), and there is uncertainty over whether it may contribute to a decline in cognitive function and/or mood by altering neurotransmitter metabolism. The aim of this work was to evaluate the impact of nitisinone on...

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Detalles Bibliográficos
Autores principales: Davison, Andrew S., Norman, Brendan P., Sutherland, Hazel, Milan, Anna M., Gallagher, James A., Jarvis, Jonathan C., Ranganath, Lakshminarayan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230570/
https://www.ncbi.nlm.nih.gov/pubmed/35736410
http://dx.doi.org/10.3390/metabo12060477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230570/
https://www.ncbi.nlm.nih.gov/pubmed/35736410
http://dx.doi.org/10.3390/metabo12060477

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