(68)Ga-Labeled [Leu(13)ψThz(14)]Bombesin(7–14) Derivatives: Promising GRPR-Targeting PET Tracers with Low Pancreas Uptake

The gastrin-releasing peptide receptor (GRPR) is a G-protein-coupled receptor that is overexpressed in many solid cancers and is a promising target for cancer imaging and therapy. However, high pancreas uptake is a major concern in the application of reported GRPR-targeting radiopharmaceuticals, par...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Lei, Zhang, Zhengxing, Merkens, Helen, Zeisler, Jutta, Zhang, Chengcheng, Roxin, Aron, Tan, Ruiyan, Bénard, François, Lin, Kuo-Shyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230575/
https://www.ncbi.nlm.nih.gov/pubmed/35744904
http://dx.doi.org/10.3390/molecules27123777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230575/
https://www.ncbi.nlm.nih.gov/pubmed/35744904
http://dx.doi.org/10.3390/molecules27123777

Ejemplares similares