Structural Dynamics of the SARS-CoV-2 Spike Protein: A 2-Year Retrospective Analysis of SARS-CoV-2 Variants (from Alpha to Omicron) Reveals an Early Divergence between Conserved and Variable Epitopes

We analyzed the epitope evolution of the spike protein in 1,860,489 SARS-CoV-2 genomes. The structural dynamics of these epitopes was determined by molecular modeling approaches. The D614G mutation, selected in the first months of the pandemic, is still present in currently circulating SARS-CoV-2 st...

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Detalles Bibliográficos
Autores principales: Guérin, Patrick, Yahi, Nouara, Azzaz, Fodil, Chahinian, Henri, Sabatier, Jean-Marc, Fantini, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230616/
https://www.ncbi.nlm.nih.gov/pubmed/35744971
http://dx.doi.org/10.3390/molecules27123851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230616/
https://www.ncbi.nlm.nih.gov/pubmed/35744971
http://dx.doi.org/10.3390/molecules27123851

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