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Polymeric Microparticles: Synthesis, Characterization and In Vitro Evaluation for Pulmonary Delivery of Rifampicin

Rifampicin, a potent broad-spectrum antibiotic, remains the backbone of anti-tubercular therapy. However, it can cause severe hepatotoxicity when given orally. To overcome the limitations of the current oral therapy, this study designed inhalable spray-dried, rifampicin-loaded microparticles using a...

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Detalles Bibliográficos
Autores principales: Naz, Faiqa Falak, Shah, Kifayat Ullah, Niazi, Zahid Rasul, Zaman, Mansoor, Lim, Vuanghao, Alfatama, Mulham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230634/
https://www.ncbi.nlm.nih.gov/pubmed/35746067
http://dx.doi.org/10.3390/polym14122491