Discovery of Novel Quinazoline Derivatives as Potent Antitumor Agents

In this work, we designed and synthesized a novel series of quinazoline derivatives 6–19 and then evaluated their broad-spectrum antitumor activity against MGC-803, MCF-7, PC-9, A549, and H1975, respectively. Most of them demonstrated low micromolar cytotoxicity towards five tested cell lines. In pa...

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Detalles Bibliográficos
Autores principales: Niu, Zhenxi, Ma, Shuli, Zhang, Lei, Liu, Qibing, Zhang, Shengnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230651/
https://www.ncbi.nlm.nih.gov/pubmed/35745027
http://dx.doi.org/10.3390/molecules27123906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230651/
https://www.ncbi.nlm.nih.gov/pubmed/35745027
http://dx.doi.org/10.3390/molecules27123906

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