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In Silico Prediction of Plasmodium falciparum Cytoadherence Inhibitors That Disrupt Interaction between gC1qR-DBLβ12 Complex

Malaria causes about half a million deaths per year, mainly in children below 5 years of age. Cytoadherence of Plasmodium falciparum infected erythrocytes in brain and placenta has been linked to severe malaria and malarial related deaths. Cytoadherence is mediated by binding of human receptor gC1qR...

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Detalles Bibliográficos
Autores principales: Hafiz, Abdul, Bakri, Rowaida, Alsaad, Mohammad, Fetni, Obadah M., Alsubaihi, Lojain I., Shamshad, Hina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230678/
https://www.ncbi.nlm.nih.gov/pubmed/35745611
http://dx.doi.org/10.3390/ph15060691