Neuraminidase (NA) 370-Loop Mutations of the 2009 Pandemic H1N1 Viruses Affect NA Enzyme Activity, Hemagglutination Titer, Mouse Virulence, and Inactivated-Virus Immunogenicity

Hemagglutinin (HA) and neuraminidase (NA) are the two major envelope proteins of influenza viruses. The spatial organization of HA and NA on the virus surface needs to be optimized to promote viral fitness, host specificity, transmissibility, infectivity, and virulence. We previously demonstrated th...

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Detalles Bibliográficos
Autores principales: Chen, Ting-Hsuan, Chen, Chung-Chu, Wu, Suh-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230709/
https://www.ncbi.nlm.nih.gov/pubmed/35746775
http://dx.doi.org/10.3390/v14061304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230709/
https://www.ncbi.nlm.nih.gov/pubmed/35746775
http://dx.doi.org/10.3390/v14061304

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