Pore-Forming Cardiotoxin VVA2 (Volvatoxin A2) Variant I82E/L86K Is an Atypical Duplex-Specific Nuclease

VVA2 (volvatoxin A chain 2) is a cardiotoxic protein purified from Volvariella volvacea. Its biological activities include hemolysis, writhing reaction, neurotoxicity, and ventricular systolic arresting activity. The cytotoxicity of VVA2 was mainly considered due to its pore-forming activity. Here w...

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Detalles Bibliográficos
Autores principales: Lu, Jia-Qi, Shou, Jia-Wen, Lo, Ka-Ching, Tang, Yun-Sang, Shi, Wei-Wei, Shaw, Pang-Chui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230820/
https://www.ncbi.nlm.nih.gov/pubmed/35737053
http://dx.doi.org/10.3390/toxins14060392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230820/
https://www.ncbi.nlm.nih.gov/pubmed/35737053
http://dx.doi.org/10.3390/toxins14060392

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