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Evaluation of Syrosingopine, an MCT Inhibitor, as Potential Modulator of Tumor Metabolism and Extracellular Acidification

Extracellular acidification has been shown to be an important characteristic of invasive tumors, as it promotes invasion and migration but also resistance to treatments. Targeting transporters involved in the regulation of tumor pH constitutes a promising anti-tumor approach, as it would disrupt cel...

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Detalles Bibliográficos
Autores principales: Buyse, Chloe, Joudiou, Nicolas, Warscotte, Aude, Richiardone, Elena, Mignion, Lionel, Corbet, Cyril, Gallez, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230831/
https://www.ncbi.nlm.nih.gov/pubmed/35736489
http://dx.doi.org/10.3390/metabo12060557