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Tyrosine 146 of the Human Na(+)/Taurocholate Cotransporting Polypeptide (NTCP) Is Essential for Its Hepatitis B Virus (HBV) Receptor Function and HBV Entry into Hepatocytes

Na(+)/taurocholate cotransporting polypeptide (NTCP, gene symbol SLC10A1) is a hepatic bile acid uptake carrier participating in the enterohepatic circulation of bile acids. Apart from its transporter function, NTCP acts as the high-affinity liver-specific receptor for the hepatitis B virus (HBV), w...

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Detalles Bibliográficos
Autores principales: Zakrzewicz, Dariusz, Leidolf, Regina, Kunz, Sebastian, Müller, Simon Franz, Neubauer, Anita, Leiting, Silke, Goldmann, Nora, Lehmann, Felix, Glebe, Dieter, Geyer, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230856/
https://www.ncbi.nlm.nih.gov/pubmed/35746730
http://dx.doi.org/10.3390/v14061259