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Tyrosine 146 of the Human Na(+)/Taurocholate Cotransporting Polypeptide (NTCP) Is Essential for Its Hepatitis B Virus (HBV) Receptor Function and HBV Entry into Hepatocytes
Na(+)/taurocholate cotransporting polypeptide (NTCP, gene symbol SLC10A1) is a hepatic bile acid uptake carrier participating in the enterohepatic circulation of bile acids. Apart from its transporter function, NTCP acts as the high-affinity liver-specific receptor for the hepatitis B virus (HBV), w...
Autores principales: | Zakrzewicz, Dariusz, Leidolf, Regina, Kunz, Sebastian, Müller, Simon Franz, Neubauer, Anita, Leiting, Silke, Goldmann, Nora, Lehmann, Felix, Glebe, Dieter, Geyer, Joachim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230856/ https://www.ncbi.nlm.nih.gov/pubmed/35746730 http://dx.doi.org/10.3390/v14061259 |
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