Investigation of the Uptake and Transport of Two Novel Camptothecin Derivatives in Caco-2 Cell Monolayers

Irinotecan and Topotecan are two Camptothecin derivatives (CPTs) whose resistance is associated with the high expression of breast cancer resistance protein (BCRP) and P-glycoprotein (P-gp). To reverse this resistance, two novel CPTs, FL77-28 (7-(3-Fluoro-4-methylphenyl)-10,11-methylenedioxy-20(S)-C...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yi, Zhang, Xiangli, Zhuang, Wenya, Yu, Yanlei, Sun, Xuanrong, Wang, Hong, Li, Fengzhi, Li, Qingyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230870/
https://www.ncbi.nlm.nih.gov/pubmed/35744795
http://dx.doi.org/10.3390/molecules27123669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230870/
https://www.ncbi.nlm.nih.gov/pubmed/35744795
http://dx.doi.org/10.3390/molecules27123669

Ejemplares similares