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Investigation of the Uptake and Transport of Two Novel Camptothecin Derivatives in Caco-2 Cell Monolayers

Irinotecan and Topotecan are two Camptothecin derivatives (CPTs) whose resistance is associated with the high expression of breast cancer resistance protein (BCRP) and P-glycoprotein (P-gp). To reverse this resistance, two novel CPTs, FL77-28 (7-(3-Fluoro-4-methylphenyl)-10,11-methylenedioxy-20(S)-C...

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Detalles Bibliográficos
Autores principales:	Wang, Yi, Zhang, Xiangli, Zhuang, Wenya, Yu, Yanlei, Sun, Xuanrong, Wang, Hong, Li, Fengzhi, Li, Qingyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230870/ https://www.ncbi.nlm.nih.gov/pubmed/35744795 http://dx.doi.org/10.3390/molecules27123669

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