Pharmacokinetic Modeling of Hydrocortisone by Including Protein Binding to Corticosteroid-Binding Globulin

Background: Patients with adrenal insufficiency are treated with oral hydrocortisone (HC) to compensate for the loss of endogenous cortisol production. Intrinsic imperfections of cortisol replacement strategies in mimicking normal cortisol secretion are the underlying cause of the increased morbidit...

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Detalles Bibliográficos
Autores principales: Rozenveld, Eric, Punt, Nieko, van Faassen, Martijn, van Beek, André P., Touw, Daan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231005/
https://www.ncbi.nlm.nih.gov/pubmed/35745734
http://dx.doi.org/10.3390/pharmaceutics14061161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231005/
https://www.ncbi.nlm.nih.gov/pubmed/35745734
http://dx.doi.org/10.3390/pharmaceutics14061161

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