Spider Toxin SNX-482 Gating Modifier Spontaneously Partitions in the Membrane Guided by Electrostatic Interactions

Spider toxin SNX-482 is a cysteine-rich peptide that interferes with calcium channel activity by binding to voltage-sensing domains of the Ca(V)2.3 subtype. Two mechanisms dominate the binding process of cysteine-rich peptides: direct binding from the aqueous phase or through lateral diffusion from...

Descripción completa

Detalles Bibliográficos
Autores principales: Mellado, Guido, Espinoza, Nicolas, Garate, Jose Antonio, Neely, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231009/
https://www.ncbi.nlm.nih.gov/pubmed/35736302
http://dx.doi.org/10.3390/membranes12060595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231009/
https://www.ncbi.nlm.nih.gov/pubmed/35736302
http://dx.doi.org/10.3390/membranes12060595

Ejemplares similares