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Trichoderma Enzymes for Degradation of Aflatoxin B1 and Ochratoxin A
The contamination of agricultural products with mycotoxins causes risks to animal and human health and severe economic losses. Mycotoxicoses can be reduced by preventing fungal infection using chemical and biological approaches. The chemical strategies can release toxic molecules; therefore, strateg...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231114/ https://www.ncbi.nlm.nih.gov/pubmed/35745082 http://dx.doi.org/10.3390/molecules27123959 |
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author | Dini, Irene Alborino, Vittoria Lanzuise, Stefania Lombardi, Nadia Marra, Roberta Balestrieri, Anna Ritieni, Alberto Woo, Sheridan L. Vinale, Francesco |
author_facet | Dini, Irene Alborino, Vittoria Lanzuise, Stefania Lombardi, Nadia Marra, Roberta Balestrieri, Anna Ritieni, Alberto Woo, Sheridan L. Vinale, Francesco |
author_sort | Dini, Irene |
collection | PubMed |
description | The contamination of agricultural products with mycotoxins causes risks to animal and human health and severe economic losses. Mycotoxicoses can be reduced by preventing fungal infection using chemical and biological approaches. The chemical strategies can release toxic molecules; therefore, strategies for biological control are being evaluated, such as using nontoxic fungi and their metabolites. This work evaluated the effect of exoenzymes produced by the beneficial fungus Trichoderma afroharzianum strain T22 in degrading Aflatoxin B1 (AFB1) and Ochratoxin A (OTA). The ability of Trichoderma to produce hydrolases was stimulated by using different inducing substrates. The highest AFB1 and OTA degradation activity was obtained using a medium containing lyophilized mushrooms and crude fiber. The T. afroharzianum T22’s ability to reduce mycotoxins may be attributed to peroxidase enzymes. This study showed that T. afroharzianum strain T22 or its peroxidase supplementation could represent a sustainable strategy for the degradation of AFB1 and OTA in feed and food products. |
format | Online Article Text |
id | pubmed-9231114 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-92311142022-06-25 Trichoderma Enzymes for Degradation of Aflatoxin B1 and Ochratoxin A Dini, Irene Alborino, Vittoria Lanzuise, Stefania Lombardi, Nadia Marra, Roberta Balestrieri, Anna Ritieni, Alberto Woo, Sheridan L. Vinale, Francesco Molecules Article The contamination of agricultural products with mycotoxins causes risks to animal and human health and severe economic losses. Mycotoxicoses can be reduced by preventing fungal infection using chemical and biological approaches. The chemical strategies can release toxic molecules; therefore, strategies for biological control are being evaluated, such as using nontoxic fungi and their metabolites. This work evaluated the effect of exoenzymes produced by the beneficial fungus Trichoderma afroharzianum strain T22 in degrading Aflatoxin B1 (AFB1) and Ochratoxin A (OTA). The ability of Trichoderma to produce hydrolases was stimulated by using different inducing substrates. The highest AFB1 and OTA degradation activity was obtained using a medium containing lyophilized mushrooms and crude fiber. The T. afroharzianum T22’s ability to reduce mycotoxins may be attributed to peroxidase enzymes. This study showed that T. afroharzianum strain T22 or its peroxidase supplementation could represent a sustainable strategy for the degradation of AFB1 and OTA in feed and food products. MDPI 2022-06-20 /pmc/articles/PMC9231114/ /pubmed/35745082 http://dx.doi.org/10.3390/molecules27123959 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Dini, Irene Alborino, Vittoria Lanzuise, Stefania Lombardi, Nadia Marra, Roberta Balestrieri, Anna Ritieni, Alberto Woo, Sheridan L. Vinale, Francesco Trichoderma Enzymes for Degradation of Aflatoxin B1 and Ochratoxin A |
title | Trichoderma Enzymes for Degradation of Aflatoxin B1 and Ochratoxin A |
title_full | Trichoderma Enzymes for Degradation of Aflatoxin B1 and Ochratoxin A |
title_fullStr | Trichoderma Enzymes for Degradation of Aflatoxin B1 and Ochratoxin A |
title_full_unstemmed | Trichoderma Enzymes for Degradation of Aflatoxin B1 and Ochratoxin A |
title_short | Trichoderma Enzymes for Degradation of Aflatoxin B1 and Ochratoxin A |
title_sort | trichoderma enzymes for degradation of aflatoxin b1 and ochratoxin a |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231114/ https://www.ncbi.nlm.nih.gov/pubmed/35745082 http://dx.doi.org/10.3390/molecules27123959 |
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