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Polymeric Micelles with pH-Responsive Cross-Linked Core Enhance In Vivo mRNA Delivery

Messenger RNA (mRNA) is emerging as a promising therapeutic modality for a variety of diseases. Because of the fragility and limited intracellular access of mRNA, the development of delivery technologies is essential for promoting the applicability of mRNA-based treatments. Among effective nanocarri...

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Detalles Bibliográficos
Autores principales: Yang, Wenqian, Chen, Pengwen, Boonstra, Eger, Hong, Taehun, Cabral, Horacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231146/
https://www.ncbi.nlm.nih.gov/pubmed/35745778
http://dx.doi.org/10.3390/pharmaceutics14061205