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Alisol B Alleviates Hepatocyte Lipid Accumulation and Lipotoxicity via Regulating RARα-PPARγ-CD36 Cascade and Attenuates Non-Alcoholic Steatohepatitis in Mice

Non-alcoholic steatohepatitis (NASH) is a common chronic liver disease worldwide, with no effective therapies available. Discovering lead compounds from herb medicine might be a valuable strategy for the treatment of NASH. Here, we discovered Alisol B, a natural compound isolated from Alisma orienta...

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Detalles Bibliográficos
Autores principales: Zhao, Zhuohui, Deng, Zhen-Tao, Huang, Suling, Ning, Mengmeng, Feng, Ying, Shen, Yu, Zhao, Qin-Shi, Leng, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231195/
https://www.ncbi.nlm.nih.gov/pubmed/35745142
http://dx.doi.org/10.3390/nu14122411